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Updated: May 10, 2026

A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
[Use of human fibrin glue for perforated trophic retinal ulcer]
1Augenklinik, RWTH Aachen, Pauwelsstr. 30, 52057, Aachen, Deutschland, aroepke@gmx.de.
Abstract:
A patient with a sterile trophic corneal perforation of 2 mm after cataract surgery underwent perforation closure with human fibrin glue. Whitening of the fibrin glue indicated a stable perforation closure 10 min after application. Perforation closure was successfully performed using human fibrin glue with complete epithelialization 2 weeks after surgery. Corneal perforation closure of sterile corneal ulcerations using human fibrin glue is a simple technique that may be successful in acute cases which have an increased risk of corneal transplant rejection.

