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Updated: May 10, 2026
09:14
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Uncontrollable haemorrhage following dabigatran prophylaxis
Pavandeep Singh Sandhu1, Caroline Wilson, Emily Dalton
1Department of Anaesthetics, Stoke Mandeville Hospital, Bucks, UK. pavansingh@doctors.org.uk
BMJ Case Reports
|June 14, 2013
Summary
An elderly patient on dabigatran anticoagulation developed a perforated viscus after hip surgery. Despite surgical repair and intensive care, massive hemorrhage led to a fatal outcome, highlighting potential complications.
Area of Science:
- Gastroenterology
- Surgical Complications
- Pharmacology
Background:
- Elderly patient undergoing total hip replacement.
- Postoperative anticoagulation therapy with dabigatran.
- History of recent major orthopedic surgery.
Observation:
- Presentation with acute abdominal pain, malaena, and haematemesis.
- Diagnosis of a perforated viscus.
- Underwent emergency laparotomy for surgical repair.
Findings:
- Massive intraoperative hemorrhage occurred during perforation repair.
- Required intensive care unit admission postoperatively.
- Deterioration despite aggressive medical management.
Implications:
- Highlights the critical risk of gastrointestinal complications in patients on anticoagulation.
- Underscores the importance of vigilant monitoring for bleeding events post-surgery.
- Emphasizes the challenges in managing massive hemorrhage in anticoagulated elderly patients.
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