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Updated: May 10, 2026

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model
Published on: June 4, 2021
Cardiac papillary fibroelastoma presenting as acute stroke
Atif Saleem Abbasi1, Mark Da Costa, Terry Hennessy
1Department of Cardiology, University Hospital Limerick, Limerick, Ireland. atifabbasi655@hotmail.com
Insights
A young woman experienced an acute stroke, later diagnosed as a cardiac papillary fibroelastoma on her mitral valve. Surgical removal led to full recovery, highlighting this rare tumor as a potential stroke cause.
Area of Science:
- Cardiology
- Neurology
- Pathology
Background:
- Cerebrovascular events in young adults often lack clear risk factors.
- Cardiac tumors are an uncommon cause of embolic stroke.
Observation:
- A young woman presented with acute stroke symptoms without typical risk factors.
- Echocardiography revealed a mass on the mitral valve anterior leaflet.
- Transesophageal echocardiography confirmed a cardiac tumor.
Findings:
- Histopathology confirmed the mitral valve mass as a cardiac papillary fibroelastoma.
- The patient underwent successful surgical resection of the tumor.
Implications:
- Cardiac papillary fibroelastoma should be considered in young stroke patients.
- Early diagnosis and surgical intervention can lead to complete recovery.
- This case underscores the importance of cardiac imaging in cryptogenic stroke evaluation.
Abstract:
We present a case of a young woman who was initially diagnosed with acute stroke with no obvious risk factors. Preliminary investigation with transthoracic echocardiography and subsequent advanced imaging with transoesophageal echocardiography suggested the diagnosis of a benign cardiac tumour on the anterior leaflet of mitral valve. The patient underwent urgent surgical resection. Histology confirmed the diagnosis of cardiac papillary fibroelastoma. She made complete clinical recovery with no recurrence of symptoms.
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