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Cumulative risk assessment toolbox: methods and approaches for the practitioner
Margaret M Macdonell1, Lynne A Haroun, Linda K Teuschler
1Environmental Science Division, Argonne National Laboratory, Argonne, IL 60439, USA.
Journal of Toxicology
|June 14, 2013
Summary
Assessing environmental chemical health risks historically focused on single substances. This work introduces a US Environmental Protection Agency toolbox with nearly 80 resources to support cumulative risk assessments for contaminated sites.
Area of Science:
- Environmental Health
- Risk Assessment
- Toxicology
Background:
- Traditional health risk assessments evaluate environmental chemicals individually, which is insufficient given daily multi-chemical exposures.
- Implementation of advanced risk assessment methods lags due to limited practitioner awareness of available tools and resources.
Purpose of the Study:
- To highlight resources from the US Environmental Protection Agency's cumulative risk toolbox for contaminated sites.
- To provide practical application notes and updates for cumulative risk assessments.
Main Methods:
- The paper reviews nearly 80 resources from the EPA's cumulative risk toolbox.
- Resources are organized according to key elements of the risk assessment process: planning, environmental fate, exposure, toxicity, and risk characterization.
Main Results:
- The toolbox offers practical guidance and resources for conducting cumulative risk assessments.
- Selected updates and practical notes enhance the utility of the resources for real-world applications.
Conclusions:
- The EPA's cumulative risk toolbox provides essential resources for practitioners conducting environmental health risk assessments.
- Future plans include expanding the toolbox to address nonchemical stressors and applications beyond contaminated sites, supporting evolving cumulative risk analyses.
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