Analysis of heart transplant survival data using generalized additive models
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Updated: May 10, 2026

A Modified Method for Heterotopic Mouse Heart Transplantion
Published on: June 23, 2014
Masaaki Tsujitani1, Yusuke Tanaka
1Department of Engineering Informatics, Osaka Electro-Communication University, Osaka 572-8530, Japan. ekaaf900@ricv.zaq.ne.jp
Abstract:
The Stanford Heart Transplant data were collected to model survival in patients using penalized smoothing splines for covariates whose values change over the course of the study. The basic idea of the present study is to use a logistic regression model and a generalized additive model with B-splines to estimate the survival function. We model survival time as a function of patient covariates and transplant status and compare the results obtained using smoothing spline, partial logistic, Cox's proportional hazards, and piecewise exponential models.
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