Controlled rapid sequence induction and intubation - an analysis of 1001 children

Diego Neuhaus1, Achim Schmitz, Andreas Gerber

  • 1Department of Anesthesia, University Children's Hospital, Zurich, Switzerland. diego.neuhaus@kispi.uzh.ch

Insights

Controlled rapid sequence induction and intubation (cRSII) with gentle facemask ventilation is a safer pediatric airway management technique. This method supports stable cardiorespiratory conditions and minimizes aspiration risk in children.

Area of Science:

  • Pediatric Anesthesiology
  • Airway Management
  • Critical Care Medicine

Background:

  • Classic rapid sequence induction poses risks for pediatric patients due to limited apnea tolerance.
  • Gentle facemask ventilation before intubation, as in controlled rapid sequence induction and intubation (cRSII), may offer a safer alternative.
  • Pediatric patients require specialized approaches for airway management during anesthesia induction.

Purpose of the Study:

  • To evaluate the safety and efficacy of controlled rapid sequence induction and intubation (cRSII) in a large pediatric cohort.
  • To analyze cardiorespiratory parameters, intubation conditions, and adverse events associated with cRSII.
  • To determine the incidence of gastric regurgitation and pulmonary aspiration during cRSII in children.

Main Methods:

  • Retrospective cohort analysis of 1001 pediatric patients undergoing cRSII.
  • Standardized institutional protocol for cRSII from 2007 to 2011.
  • Review of electronic patient data for vital signs, intubation success, and respiratory events.

Main Results:

  • cRSII demonstrated a low incidence of hypoxemia (0.8% combined moderate/severe).
  • No bradycardia or hypotension occurred; gastric regurgitation was rare (0.1%) with no pulmonary aspiration.
  • Difficult intubation occurred in only 0.5% of patients, with no evidence of silent aspiration.

Conclusions:

  • Controlled rapid sequence induction and intubation (cRSII) with pre-intubation ventilation ensures stable cardiorespiratory status in pediatric patients.
  • This technique is effective for airway management, even in children with a full stomach.
  • cRSII appears to be a safe method with a low risk of pulmonary aspiration in pediatric anesthesia.
Abstract