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Prevention of sevoflurane delirium and agitation with propofol

Zakaria Messieha1

  • 1University of Illinois at Chicago, Chicago, Illinois, USA. messieha@uic.edu

Anesthesia Progress
|June 15, 2013
PubMed

Insights

Emergence delirium and agitation (EAD) in children receiving sevoflurane anesthesia is common. A novel Bispectral Index System (BIS)-guided propofol washout technique effectively prevents EAD, improving patient safety and satisfaction.

Area of Science:

  • Anesthesiology
  • Pediatric Medicine
  • Neuroscience

Background:

  • Emergence delirium and agitation (EAD) are frequent complications in pediatric patients undergoing sevoflurane anesthesia.
  • These events increase the risk of injury and reduce parental satisfaction, particularly in outpatient settings.

Purpose of the Study:

  • To review existing literature on EAD prevention strategies in children.
  • To propose and evaluate a novel Bispectral Index System (BIS)-guided anesthesia technique with propofol washout for EAD prevention.

Main Methods:

  • Literature review of EAD management strategies.
  • Proposal of a Bispectral Index System (BIS)-guided anesthesia protocol utilizing propofol washout.

Main Results:

  • Sevoflurane anesthesia commonly causes EAD in pediatric patients.
  • The proposed BIS-guided propofol washout technique is presented as a potentially effective method for EAD prevention.

Conclusions:

  • EAD is a significant concern in pediatric anesthesia.
  • A BIS-guided propofol washout technique offers a promising approach to mitigate EAD, enhancing safety and satisfaction.

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