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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

[Radiation therapy in thyroid cancer].

X S Sun¹, N Guevara, N Fakhry

¹Département de radiothérapie, centre hospitalier régional universitaire de Besançon, 2, boulevard Fleming, 25030 Besançon, France.

Cancer Radiotherapie : Journal De La Societe Francaise De Radiotherapie Oncologique

|June 15, 2013

Summary

External beam radiation therapy is crucial for anaplastic thyroid cancer and indicated in specific differentiated thyroid cancer cases. Intensity-modulated radiation therapy (IMRT) improves outcomes by reducing toxicity.

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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Area of Science:

Oncology
Radiation Oncology
Medical Physics

Context:

Anaplastic thyroid cancer (ATC) has a poor prognosis despite treatment.
Differentiated thyroid carcinomas (DTCs) generally have good prognoses, with limited roles for external beam radiation therapy (EBRT).
Insular and medullary thyroid carcinomas present intermediate prognoses and are infrequently irradiated.

Purpose:

To update recommendations for EBRT in various thyroid cancer subtypes.
To highlight the advantages of novel radiation techniques in thyroid cancer management.

Summary:

Non-mutilating surgery followed by EBRT is standard for ATC, often with chemotherapy.
EBRT is considered for specific DTCs (iodine-negative, incompletely resected, older age, aggressive variants) and medullary thyroid cancer.
Intensity-modulated radiation therapy (IMRT) offers superior tumor coverage and organ sparing, reducing late toxicities to under 5%.

Impact:

IMRT is becoming a standard of care, improving the role of radiation therapy in ATC multimodal strategies and DTC management.
Refined criteria for EBRT in DTCs, considering histological variants and patient age.
Reduced radiation therapy morbidity allows for broader application of EBRT in select thyroid cancer cases.