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Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty

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Published on: July 24, 2013

Frailty consensus: a call to action.

John E Morley¹, Bruno Vellas, G Abellan van Kan

¹Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. morley@slu.edu

Journal of the American Medical Directors Association

|June 15, 2013

Summary

This summary is machine-generated.

Physical frailty is a medical syndrome increasing vulnerability to death or dependency. Early screening and interventions like exercise can help manage this condition in older adults.

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Area of Science:

Gerontology
Clinical Medicine
Public Health

Background:

Frailty is a clinical state of increased vulnerability to stressors, leading to dependency or mortality.
It arises from diverse diseases and medical conditions, impacting physiological function.
Physical frailty, a specific type, is defined by diminished strength, endurance, and reduced physiological function.

Framework:

A consensus defined physical frailty as a medical syndrome with multiple causes.
Key characteristics include diminished strength, endurance, and reduced physiologic function.
This syndrome heightens vulnerability to increased dependency and/or death.

Implementation:

Physical frailty is potentially preventable or treatable.
Effective interventions include exercise, protein-calorie supplementation, vitamin D, and reducing polypharmacy.
Simple, validated screening tests like the FRAIL scale aid objective recognition.

Implications:

Screening for frailty is recommended for individuals over 70 years old.
Screening is also advised for those with significant weight loss (>5%) due to chronic disease.
Early identification and management are crucial for optimizing patient outcomes and reducing healthcare burdens.