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Published on: November 25, 2025
Gallstone ileus: revisiting surgical outcomes using National Surgical Quality Improvement Program data
Mohan K Mallipeddi1, Theodore N Pappas, Mark L Shapiro
1Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA. mohan.mallipeddi@duke.edu
Surgical treatment for gallstone ileus is less morbid than previously thought. Concurrent cholecystectomy with enterolithotomy did not increase mortality but led to more complications and longer hospital stays.
Area of Science:
- Gastroenterology
- Surgical Outcomes
- Gallstone Ileus Management
Background:
- Gallstone ileus surgical management is standard, but optimal approach is debated.
- Previous studies relied on small, single-center data.
- Need for larger studies on surgical outcomes for gallstone ileus.
Purpose of the Study:
- Review outcomes of surgical gallstone ileus management.
- Determine if cholecystectomy plus enterolithotomy increases morbidity/mortality.
Main Methods:
- Analyzed 127 patients (2005-2010) from ACS NSQIP database.
- Compared outcomes of enterolithotomy alone vs. with cholecystectomy.
- Assessed demographics, comorbidities, operative time, and 30-day outcomes.
Main Results:
- Overall 30-day morbidity was 35.4%, mortality 5.5%.
- No significant mortality difference between groups (5.3% vs. 7.1%).
- Cholecystectomy group had more minor complications and longer hospitalization.
Conclusions:
- Modern surgical gallstone ileus treatment is less morbid than previously reported.
- Concurrent cholecystectomy does not improve mortality.
- Insufficient evidence supports routine concurrent cholecystectomy for gallstone ileus.
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