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Related Experiment Video

Updated: May 10, 2026

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

Stroke warning syndrome: 18 new cases.

Rossana Tassi¹, Alfonso Cerase, Maurizio Acampa

¹Stroke Unit, Department of Neurological and Sensorineural Sciences, Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte, Siena, Italy. r.tassi@ao-siena.toscana.it

Journal of the Neurological Sciences

|June 15, 2013

Summary

Stroke warning syndrome (SWS) is a rare condition. This study found IV-rtPA treatment for SWS showed lower efficacy and no added benefit for stroke patients.

Keywords:

Capsular warning syndrome Intravenous thrombolysis Pontine warning syndrome Small vessel diseases Stroke warning syndrome Transient ischemic attack

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Last Updated: May 10, 2026

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

Area of Science:

Neurology
Stroke Medicine
Clinical Research

Background:

Stroke warning syndrome (SWS) is a rare condition preceding ischemic stroke.
SWS presents with recurrent transient focal neurological deficits.
Clinical and neuroimaging findings classify SWS as capsular, pontine, or callosal.

Purpose of the Study:

Evaluate the prevalence of SWS in ischemic stroke patients.
Compare outcomes between SWS patients treated with IV-rtPA and those receiving other therapies.

Main Methods:

Retrospective analysis of 967 ischemic stroke patients admitted between April 2008 and January 2013.
Identified 18 patients with SWS, divided into IV-rtPA (n=9) and non-IV-rtPA (n=9) groups.
Assessed 3-month outcomes using the modified Rankin Scale.

Main Results:

SWS prevalence was 1.8% in the studied ischemic stroke population.
Hypertension and dyslipidemia were common risk factors in both groups.
Good outcomes (mRS 0-2) were observed in 33% of the IV-rtPA group versus 55% of the non-IV-rtPA group.

Conclusions:

SWS is an under-recognized neurological syndrome.
Intravenous rt-PA may have reduced efficacy in SWS compared to other stroke types.
No hemorrhagic complications were observed in SWS patients treated with IV-rtPA.