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Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
05:56

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting

Published on: June 21, 2024

Gabapentin for Postoperative Vomiting in Children Requiring Posterior Fossa Tumor Resection

Ko-Chun Tsai1, Yung-Li Yang2, Pi-Chuan Fan3

  • 1Division of Pediatric, Taipei Hospital, Department of Health, Taipei, Taiwan; Division of Neurology, Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.

Pediatrics and Neonatology
|June 15, 2013
PubMed

Insights

Gabapentin effectively treated refractory nausea and vomiting in pediatric patients after craniotomy for medulloblastoma. This suggests gabapentin as a potential novel antiemetic therapy for similar cases.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Pediatric Oncology

Background:

  • Gabapentin is recognized for its analgesic and antiepileptic properties.
  • Its antiemetic potential, particularly in pediatric neurosurgery patients, remains under-explored.

Observation:

  • Two children with medulloblastoma experienced severe, refractory postoperative nausea and vomiting (PONV) after craniotomy.
  • Conventional antiemetic treatments failed to provide relief for their symptoms.

Findings:

  • Gabapentin administration led to complete resolution of nausea and vomiting in both pediatric patients.
  • Symptoms improved from multiple daily episodes to zero episodes after gabapentin treatment.

Implications:

  • Gabapentin may represent a novel therapeutic option for managing refractory PONV in pediatric patients.
  • Further research into gabapentin's antiemetic effects in neurosurgical contexts is warranted.

Keywords:
gabapentinpost-operative vomitingposterior fossa tumor

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