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Related Concept Videos

Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...

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Updated: May 10, 2026

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

Expanding HIV testing: back to the future.

Bernard M Branson1, Abigail Viall, Elizabeth Marum

  • 1Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. BBranson@cdc.gov

Journal of Acquired Immune Deficiency Syndromes (1999)
|June 15, 2013
PubMed
Summary
This summary is machine-generated.

Increased HIV testing and early diagnosis are crucial for effective treatment and reducing transmission. "Test and treat" strategies offer optimism for HIV control and elimination through widespread testing and immediate antiviral therapy.

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Last Updated: May 10, 2026

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
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Published on: October 31, 2010

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • The efficacy of antiretroviral therapy (ART) in reducing HIV transmission has been established.
  • The
  • test and treat
  • model offers a promising strategy for HIV control.
  • Scaling up HIV testing is essential for early diagnosis and treatment initiation.

Purpose of the Study:

  • To highlight the growing importance of HIV testing in the context of effective HIV treatment.
  • To emphasize the potential of
  • test and treat
  • strategies for HIV control and elimination.
  • To explore lessons learned from successful HIV testing initiatives.

Main Methods:

  • Review of evidence on the impact of ART on HIV transmission.
  • Analysis of
  • test and treat
  • models and their implications for HIV control.
  • Examination of strategies for scaling up HIV testing, drawing from global experiences.

Main Results:

  • Effective HIV treatment, particularly ART, significantly reduces transmission.
  • Widespread HIV testing, prompt diagnosis, and immediate ART access are key to achieving HIV control.
  • Successful testing scale-up approaches have often originated in resource-limited settings.

Conclusions:

  • HIV testing is a critical component of modern HIV management and prevention.
  • The
  • test and treat
  • paradigm presents a viable path towards HIV elimination.
  • Leveraging lessons from past initiatives can guide future HIV testing endeavors.