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Updated: May 1, 2026

Using Fluorescent Proteins to Monitor Glycosome Dynamics in the African Trypanosome
Published on: August 19, 2014
Transport through the Golgi in Trypanosoma brucei
1Max F. Perutz Laboratories, University of Vienna, Medical University of Vienna, Vienna, Austria. graham.warren@mfpl.ac.at
Abstract:
The mechanism of transport through the Golgi is still controversial, and this has led to a search for model organisms that might provide new insights. One such is the protozoan parasite, Trypanosoma brucei, which has a single Golgi whose major cargo is the GPI-anchored coat proteins that decorate the cell surface and protect the organism against immune attack through a shedding mechanism. Using published biochemical and stereological data, it is possible to show that some models for Golgi transport appear more likely than others.
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