Related Experiment Video
Updated: May 10, 2026
A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
A study to evaluate the efficacy of various topical treatment modalities for alopecia areata
Vidyadhar R Sardesai1, Smita Prasad, Trupti D Agarwal
1Department of Dermatology, STD and Leprosy, Bharati Vidyapeeth Deemed University Medical College, Pune, India.
Context:
Alopecia Areata (AA) is a common form of non-scarring hair disorder of unclear etiology. The disease may have serious psychological effect.
Aims:
The objective is to assess the therapeutic effect and side effects of various topical modalities for the treatment of AA.
Settings And Design:
Open, randomized, comparative study.
Materials And Methods:
For this study, 30 patients were included of all age groups and both sexes having localized (<5 patches and <25% scalp involvement) alopecia, with no underlying disease or family history, and who had not received any treatment before. They were treated sequentially with 5 different combination regimes for 3 months. The response was assessed subjectively as well as objectively by the "Severity of Alopecia Tool Score".
Statistical Analysis:
Chi-square test.
Results:
Out of the 5 modalities studied, the Intralesional and Topical Steroids were the most effective with no significant side effects.
Conclusions:
Among the various topical modalities used for the treatment of AA, the most effective are the Intralesional and Topical steroids with no significant side-effects.
