Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interstitial microwave hyperthermia applicators having submillimetre diameters.

C F Gottlieb1, M J Hagmann, T M Babij

  • 1Department of Radiation Oncology, University of Miami School of Medicine, FL 33101.

International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
|May 1, 1990
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Application of robotic stereotactic radiotherapy to peripheral stage I non-small cell lung cancer with curative intent.

Clinical oncology (Royal College of Radiologists (Great Britain))·2009
Same author

Anomalous high-frequency oscillations in a field emission tube and their significance in pulsed field emission.

Ultramicroscopy·2007
Same author

Simulation of sub-femtosecond response in laser-assisted field emission.

Ultramicroscopy·2007
Same author

Measurements of the self-sustained enhancement of field emission by carbon fiber microemitters.

Ultramicroscopy·2003
Same author

Prototypes using metal, carbon fiber and composite field emission sources modulated by a laser beam.

Ultramicroscopy·2002
Same author

Simulations of photon-assisted tunneling using the Fokker-Planck equation to model the scattering of electrons within the emitting metal tip.

Ultramicroscopy·2002

New microscopic interstitial hyperthermia applicators offer improved access for cancer treatment. These smaller devices provide effective energy deposition, suitable for deep-seated tumors and intraluminal access.

Area of Science:

  • Biomedical Engineering
  • Medical Physics
  • Oncology

Background:

  • Interstitial hyperthermia is a cancer treatment modality.
  • Existing applicators have limitations in terms of size and catheter compatibility.
  • Minimally invasive techniques are crucial for treating deep-seated tumors.

Purpose of the Study:

  • To fabricate and characterize novel, miniaturized interstitial hyperthermia applicators.
  • To evaluate the energy deposition patterns and clinical applicability of these new devices.
  • To compare the performance of new applicators with existing commercial options.

Main Methods:

  • Microscopic fabrication techniques were employed to create applicators with diameters of 0.20, 0.33, and 0.58 mm.
  • Applicator performance was assessed by measuring specific absorption rate (SAR) patterns in muscle-simulating phantoms.

Related Experiment Videos

  • Electric field intensity was measured using a miniature implantable isotropic probe (3 mm diameter).

    • Main Results:

    • The new applicators are compatible with smaller catheters (22-30 gauge) compared to commercial devices (≥17 gauge).
    • SAR patterns demonstrated similar heating characteristics across new and commercial applicators.
    • Durability and power handling capabilities were found to be adequate for clinical use.

    Conclusions:

    • Submillimetre interstitial hyperthermia applicators have been successfully developed.
    • These applicators offer improved access for treating deep-seated, intraluminal, or intravascular tumors.
    • The findings support the potential clinical utility of these miniaturized devices in cancer therapy.