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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: May 10, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

[A case of ring melanoma found while treating traumatic glaucoma].

Kazuyo Manabe¹, Nobuo Jo, Hiroko Tateno

¹Department of Ophthalmology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata-shi, Osaka-fu 573-1191, Japan. manabe.kazuyo@jp.panasonic.com

Nippon Ganka Gakkai Zasshi

|June 18, 2013

Summary

Ring melanoma, a rare ciliary body malignant melanoma, was diagnosed in a patient with traumatic glaucoma. Ultrasound biomicroscopy (UBM) aided in detecting this rare condition, crucial for differential diagnosis.

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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

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Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres

Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres

Published on: February 2, 2015

Area of Science:

Ophthalmology
Oncology

Background:

Ring melanoma, a rare malignant melanoma infiltrating over 180 degrees of the ciliary body, is infrequently observed in Japan.
This report details a case identified during the management of traumatic glaucoma.

Observation:

A 44-year-old woman presented with persistent high intraocular pressure (30 mmHg) in her left eye following blunt trauma.
Gonioscopy revealed approximately 180 degrees of angle recession, and anti-glaucoma medication proved ineffective.
Ultrasound biomicroscopy (UBM) demonstrated progressive iris elevation and 360-degree ciliary body thickening.

Findings:

Atypical cells with melanin granules were detected in the aqueous fluid.
Positron Emission Tomography-Computed Tomography (PET-CT) yielded positive findings.
Histopathological examination confirmed the diagnosis of ring melanoma after enucleation.

Implications:

Ring melanoma should be considered in the differential diagnosis of intractable secondary glaucoma.
Early detection using advanced imaging like UBM is vital for managing rare ocular tumors.