Related Experiment Video
Updated: May 10, 2026

Modified Radical Neck Dissection for Cervical Metastasis
Published on: February 20, 2026
En bloc resection of a multilevel high-cervical chordoma involving C-2: new operative modalities: technical note
Kern H Guppy1, Indro Chakrabarti, Richard S Isaacs
1Department of Neurosurgery, The Kaiser Permanente Medical Group, Sacramento, California, USA. kguppy@yahoo.com
Abstract:
En bloc resection of cervical chordomas has led to longer survival rates but has resulted in significant morbidities from the procedure, especially when the tumor is multilevel and located in the high-cervical (C1-3) region. To date, there have been only 5 reported cases of multilevel en bloc resection of chordomas in the high-cervical spine. In this technical report the authors describe a sixth case. A complete spondylectomy was performed at C-2 and C-3 with spinal reconstruction and stabilization, using several new modalities that were not used in the previous cases. The use of 1) preoperative endovascular sacrificing of the vertebral artery, 2) CT image-guidance, 3) an ultrasonic aspirator for skeletonizing the vertebral artery, and 4) the custom design of an anterior cage all contributed to absence of intraoperative or long-term (20 months) hardware failure and pseudarthrosis.