Related Experiment Video
Updated: May 10, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
Cutaneous chemical burns in children - a comparative study
Joseph Hardwicke1, Janak Bechar, Husam Bella
1Birmingham Institute for Paediatic Plastic Surgery (BIPPS), Birmingham Children's Hospital NHS Foundation Trust, Steelhouse Lane, Birmingham B4 6NH, UK; West Midlands Regional Burns Centre, University Hospitals of Birmingham NHS Foundation Trust, New Queen Elizabeth Hospital, Mindelsohn Way, Edgbaston, Birmingham B15 2WB, UK; University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Chemical burns in children are rare but increasing, often occurring domestically. While similar in severity to adult burns, they differ in body area affected and require specific awareness for prevention and care.
Area of Science:
- Pediatric Burn Care
- Toxicology
- Dermatology
Background:
- Chemical burns are an uncommon cause of cutaneous injury in pediatric patients.
- Understanding the epidemiology and characteristics of childhood chemical burns is crucial for effective management.
- Comparing pediatric chemical burns to adult cases within the same population can reveal unique patterns.
Purpose of the Study:
- To investigate the incidence and characteristics of childhood chemical burns.
- To compare pediatric chemical burns with adult chemical burns from the same geographic area.
- To identify risk factors and patterns associated with chemical burns in children.
Main Methods:
- Retrospective analysis of 2054 patients referred to a pediatric burns unit.
- Identification of 24 cases of cutaneous chemical burns in children.
- Comparison with a cohort of adult patients with chemical burns from the same population.
Main Results:
- Chemical burns accounted for 1.1% of pediatric burns, with over half occurring in domestic settings.
- Mean total body surface area (TBSA) affected was 1.9% in children, identical to adults, but with different distribution patterns (buttock/perineum in children vs. lower limb in adults).
- Children presented earlier, required less surgery, had shorter hospital stays, but received less appropriate first aid compared to adults.
Conclusions:
- Childhood chemical burns are rare but appear to be increasing regionally.
- Distinctive patterns in affected body areas and healthcare utilization exist between pediatric and adult chemical burns.
- Awareness of etiology, distribution, and risk factors, including potential child protection issues, is vital for managing pediatric chemical burns.
Related Concept Videos
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Effects of Chemicals: Overview
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

