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Renal recoverability in infants with obstructive calcular anuria: is it better than in older children?

Sameh Kotb1, Mohammed S ElSheemy, Hany A Morsi

  • 1Division of Pediatric Urology, Aboul-Riche Children's Hospital, Cairo University, Cairo, Egypt.

Journal of Pediatric Urology
|June 18, 2013
PubMed

Insights

Infants with obstructive calcular anuria can achieve full renal recovery with timely medical and surgical interventions. This age group (<2 years) shows a more favorable prognosis and lower complication rates compared to older children.

Area of Science:

  • Pediatric Nephrology
  • Pediatric Urology
  • Surgical Innovation

Background:

  • Infant urolithiasis presents significant morbidity.
  • Literature on calcular anuria in infants is scarce.
  • Evaluating interventions for renal recovery in infants is crucial.

Purpose of the Study:

  • To assess the impact of interventions on renal recoverability in infants with obstructive calcular anuria.
  • To compare outcomes in infants with older children.

Main Methods:

  • Retrospective study of 24 infants with obstructive calcular anuria.
  • Treatments included urinary diversion, endoscopic procedures (ureteroscopy, JJ stenting), and open surgery (ureterolithotomy, pyelolithotomy).
  • Mean age was 16.5 ± 6.2 months.

Main Results:

  • Mean serum creatinine was 5.8 ± 2.6 mg/dl; all normalized by discharge.
  • 11 patients (45.8%) required initial dialysis/urinary diversion.
  • Endoscopic treatment was most common (62.5%); overall complication rate was 12.5% with no mortality or chronic renal failure at 6 months.

Conclusions:

  • Timely medical and surgical management leads to full renal function recovery in infants with calcular anuria.
  • Infants (<2 years) demonstrate a more favorable renal prognosis than older children.
  • Lower complication rates and higher recovery were observed compared to older age groups.
Abstract

Keywords:
AnuriaCalculiInfantsObstructive nephropathyRenal recoverability

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