Related Experiment Video
Updated: May 10, 2026

05:52
Clinical Efficacy of Small Needle Knife Therapy on Stage I-II Frozen Shoulder
Published on: November 17, 2023
[Infusional therapy: an alternative for shouder pain post-laparoscopy]
Cielo Alborada Ureña-Frausto1, Ricardo Plancarte-Sánchez, Juan Ignacio Reyes-Torres
1Departamento de Anestesiología, Hospital General de Cerralvo, Cerralvo, Nuevo León, Mexico. cielo_urena@hotmail.com
Cirugia Y Cirujanos
|June 18, 2013
Summary
This study found that a combination of ketoprofen and tramadol, administered as infusional therapy, effectively manages shoulder pain after laparoscopic surgery. This multimodal approach offers a safe alternative to opioids, reducing the need for rescue analgesia.
Area of Science:
- Anesthesiology
- Pain Management
- Surgical Procedures
Background:
- Neuraxial anesthesia reduces complications in upper abdominal laparoscopic surgery.
- Shoulder pain is a frequent and challenging complication.
- Opioids for pain control can impair respiratory function.
Purpose of the Study:
- To compare different analgesic regimens for shoulder pain caused by pneumoperitoneum.
- To evaluate the efficacy and safety of multimodal analgesic strategies.
Main Methods:
- A nonrandomized clinical trial involving 56 patients undergoing laparoscopic cholecystectomy.
- Patients were divided into four groups receiving ketorolac, ketoprofen, or ketoprofen with varying doses of tramadol.
- Pain intensity, rescue analgesia, and operative time were analyzed.
Main Results:
- The ketorolac group experienced significantly more shoulder pain events.
- The group receiving ketoprofen 100 mg plus tramadol 100 mg required less rescue analgesia.
- No significant differences in operative time were noted between groups.
Conclusions:
- Preemptive infusional therapy with ketoprofen (100 mg) and tramadol (100 mg) is safe and effective for laparoscopic surgery.
- This multimodal approach provides superior shoulder pain control compared to other tested regimens.
- The ketoprofen-tramadol combination offers a viable alternative to opioids for managing post-operative pain.