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Published on: November 4, 2010
Childhood asthma hospitalizations in the United States, 2000-2009
Kohei Hasegawa1, Yusuke Tsugawa, David F M Brown
1Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA.
Insights
Childhood asthma hospitalizations and mortality decreased in the US from 2000 to 2009. However, mechanical ventilation use and hospital charges for pediatric asthma cases significantly increased during this period.
Area of Science:
- Pediatric Pulmonology
- Health Services Research
- Epidemiology
Background:
- Childhood asthma remains a significant public health concern in the United States.
- Understanding trends in pediatric asthma hospitalization, mortality, and treatment costs is crucial for resource allocation and healthcare policy.
- Previous research has indicated variability in asthma management outcomes over time.
Purpose of the Study:
- To analyze temporal trends in US childhood asthma hospitalizations, in-hospital mortality, mechanical ventilation use, and associated hospital charges.
- To identify changes in key pediatric asthma care indicators between 2000 and 2009.
Main Methods:
- A serial, cross-sectional analysis was conducted using the nationally representative Kids Inpatient Database (KID).
- Children aged under 18 years with asthma (ICD-9-CM code 493.xx) were identified.
- Outcome measures included asthma hospitalization incidence, in-hospital mortality, mechanical ventilation use, and hospital charges, adjusted for inflation.
Main Results:
- The rate of asthma hospitalizations in US children decreased by 13% from 2000 to 2009 (21.1 to 18.4 per 10,000 person-years).
- In-hospital mortality significantly declined (OR 0.37 for 2009 vs. 2000).
- Conversely, mechanical ventilation use increased by 28% (0.8% to 1.0%), and total hospital charges rose by 26% ($1.27 billion to $1.59 billion), driven by higher per-discharge costs.
Conclusions:
- Significant reductions in childhood asthma hospitalizations and in-hospital mortality were observed in the US between 2000 and 2009.
- Despite improved outcomes, there was a concurrent increase in the utilization of mechanical ventilation and escalating hospital charges for pediatric asthma care.
- These findings highlight a complex trend in pediatric asthma management, with progress in some areas but rising costs and resource intensity in others.
Objective:
To examine temporal trends in the US incidence of childhood asthma hospitalizations, in-hospital mortality, mechanical ventilation use, and hospital charges between 2000 and 2009.
Study Design:
This was a serial, cross-sectional analysis of a nationally representative sample of children hospitalized with acute asthma. The Kids Inpatient Database was used to identify children aged <18 years with asthma by International Classification of Diseases, Ninth Revision, Clinical Modification code 493.xx. Outcome measures were asthma hospitalization incidence, in-hospital mortality, mechanical ventilation use, and hospital charges. We examined temporal trends of each outcome, accounting for sampling weights. Hospital charges were adjusted for inflation to 2009 US dollars.
Results:
The 4 separate years (2000, 2003, 2006, and 2009) of national discharge data included a total of 592805 weighted discharges with asthma. Between 2000 and 2009, the rate of asthma hospitalization in US children decreased from 21.1 to 18.4 per 10000 person-years (13% decrease; Ptrend < .001). Mortality declined significantly after adjusting for confounders (OR for comparison of 2009 with 2000, 0.37; 95% CI, 0.17-0.79). In contrast, there was an increase in the use of mechanical ventilation (from 0.8% to 1.0%, a 28% increase; Ptrend < .001). Nationwide hospital charges also increased from $1.27 billion to $1.59 billion (26% increase; Ptrend < .001); this increase was driven by a rise in the geometric mean of hospital charges per discharge, from $5940 to $8410 (42% increase; Ptrend < .001).
Conclusion:
Between 2000 and 2009, we found significant declines in asthma hospitalization and in-hospital mortality among US children. In contrast, mechanical ventilation use and hospital charges for asthma increased significantly over this same period.
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