Related Experiment Video
Updated: May 10, 2026

How to Create Conditioned Taste Aversion for Grazing Ground Covers in Woody Crops with Small Ruminants
Published on: April 30, 2016
Reduced palatability in pain-induced conditioned taste aversions
Jian-You Lin1, Joe Arthurs, Steve Reilly
1Department of Psychology, University of Illinois at Chicago, 1007 West Harrison Street, Chicago, IL 60607, United States. jlin2@uic.edu
Abstract:
The current study investigated whether internal pain-inducing agents can modulate palatability of a tastant in the same way as illness-inducing agents (e.g., lithium chloride). Similar to traditional conditioned taste aversion (CTA) experiments, during conditioning the rats were exposed to a saccharin solution followed by intraperitoneal injections of either gallamine (Experiment 1) or hypertonic sodium chloride (NaCl; Experiments 1 and 2). In addition to the total amount consumed, the time of each lick was recorded for lick pattern analysis. The results showed that both gallamine and hypertonic NaCl caused suppression in saccharin intake. Importantly, both lick cluster size and initial lick rate (the measures of taste palatability) were reduced as well. This pattern of results suggests that these pain-inducing agents reduce the hedonic value of the associated tastant and thus CTA is acquired. The current finding serves as evidence supporting the view that CTA is a broadly tuned mechanism that can be triggered by changes in internal body states following consummatory experience.
More Related Videos
12:20Use of the Operant Orofacial Pain Assessment Device (OPAD) to Measure Changes in Nociceptive Behavior
Published on: June 10, 2013
08:07Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats
Published on: August 24, 2016
Related Concept Videos
Conditioned Taste Aversion
A notable characteristic of conditioned taste aversion is that it often requires only a single exposure...
The Physiology of Taste
Taste Buds and Receptors
Analgesia and Pain Management
Gustation
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists