Related Experiment Video
Updated: May 10, 2026
05:36
Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
Published on: February 8, 2020
Intraventricular metastatic clear cell renal carcinoma
I Sava1, Anca Sava, Elena Şapte
1Discipline of Radiology, "Grigore T. Popa" University of Medicine and Pharmacy, Iassy, Romania.
Summary
Metastatic clear cell renal carcinoma can present as a third ventricle tumor, even without a known primary malignancy. This rare intraventricular metastasis poses diagnostic challenges and requires consideration in differential diagnoses.
Area of Science:
- Neuro-oncology
- Pathology
Background:
- Intraventricular tumors present diagnostic challenges due to diverse histological types in both adult and pediatric populations.
- Accurate diagnosis is crucial for effective treatment planning and patient outcomes.
Observation:
- A 48-year-old patient presented with nausea, vomiting, headache, confusion, and drowsiness.
- Imaging revealed a third ventricle neoformation with bilateral lateral ventricles dilatation and annular enhancement.
- Surgical exploration identified a well-vascularized, firm, reddish intraventricular mass.
Findings:
- Pathologic diagnosis confirmed metastatic clear cell renal carcinoma.
- The patient experienced initial postoperative improvement followed by deterioration due to bronchopneumonia, leading to death.
Implications:
- Clear cell carcinoma metastasis to the third ventricle should be considered in patients with solitary intraventricular lesions, irrespective of a known primary tumor.
- This case highlights the importance of comprehensive diagnostic workup for intraventricular masses.
