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Small cell variant of anaplastic large cell lymphoma presenting as arm mass in a child: a rare entity with diagnostic
Sunil Pasricha1, Jatin S Gandhi, Gurudutt Gupta
1Department of Pathology. Rajiv -Gandhi Cancer -Institute & Research Centre, Sector 5, -Rohini, New Delhi, India.
Abstract:
Anaplastic lymphoma kinase positive, anaplastic large cell lymphoma (ALCL) is an uncommon T-cell non-Hodgkin lymphoma. A rare morphological variant-small cell variant of ALCL may pose diagnostic challenge especially when it presents primarily as a soft tissue mass. We present a rare case of small cell variant of ALCL in a 14-year-old female presented with arm swelling with emphasis on clinical, morphological and immunohistochemical aspects. Pathologists should be aware of this entity when considering a differential diagnosis of malignant round cell tumor as early and correct diagnosis has important clinical implications.