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[Drusen papilla with vision disorder and pathologic visual evoked potentials].

P Vieregge1, A Rosengart, E Mehdorn

  • 1Klinik für Neurologie, Medizinische Universität, Lübeck.

Der Nervenarzt
|June 1, 1990
PubMed
Summary

Optic nerve head drusen can cause visual field defects and abnormal VEP responses. Early diagnosis is crucial for patients experiencing visual disturbances, especially younger individuals requiring neurological and ophthalmological evaluation.

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Area of Science:

  • Ophthalmology
  • Neuro-ophthalmology
  • Visual Electrophysiology

Background:

  • Optic nerve head drusen are a common finding, but their clinical significance and association with visual pathway dysfunction require further elucidation.
  • Understanding the electrophysiological correlates of optic nerve head drusen is essential for accurate diagnosis and management.

Observation:

  • This report details six cases of optic nerve head drusen identified ophthalmoscopically.
  • Five out of six patients exhibited pathological latencies in their P100 visual evoked potential (VEP) responses.
  • Variable visual field defects were observed in all six patients, irrespective of subjective visual complaints.

Findings:

  • Optic nerve head drusen are frequently associated with electrophysiological abnormalities, specifically delayed P100 potentials on VEP testing.

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  • Visual field defects are a consistent finding in patients with optic nerve head drusen, even in the absence of overt symptoms.
  • A significant correlation exists between optic nerve head drusen and abnormal VEP findings.

    • Implications:

    • Optic nerve head drusen should be considered a critical differential diagnosis in patients presenting with visual disturbances and abnormal VEP results.
    • Prompt neurological and ophthalmological examination is recommended for individuals, particularly younger patients, exhibiting these signs.
    • Early identification of optic nerve head drusen can prevent misdiagnosis and ensure appropriate patient management, especially in cases with potential neurological implications.