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Related Concept Videos

Molecules with Multiple Chiral Centers02:25

Molecules with Multiple Chiral Centers

Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
Molecular Models02:00

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Molecules have characteristic shapes that are crucial for their function. The arrangement of various electron groups around the central atom dictates their molecular geometry. Electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between the electron pairs by maximizing the distance between them. The valence electrons form either bonding pairs, located primarily between bonded atoms, or lone pairs.
Two regions of electron density in a diatomic...
Mass Spectrometry: Overview01:19

Mass Spectrometry: Overview

Mass spectrometry is an analytical technique used to determine the molecular mass and molecular formula of a compound. The basic principle of mass spectrometry is to generate ions from the analyte molecule and measure these ion abundances against their molecular mass. One common type of ionization, known as electron ionization or EI, bombards the analyte molecules in the gas phase with high-energy electron beams. The electron beams displace an electron from the molecule and leave behind a...

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Spatial Separation of Molecular Conformers and Clusters
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Published on: January 9, 2014

Is the focus on "molecules" obsolete?

George M Whitesides1

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA. gwhitesides@gmwgroup.harvard.edu

Annual Review of Analytical Chemistry (Palo Alto, Calif.)
|June 19, 2013
PubMed
Summary
This summary is machine-generated.

Analytical chemistry

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Area of Science:

  • Analytical Chemistry
  • Interdisciplinary Research

Background:

  • Analytical chemistry has historically focused on detailed molecular property analysis.
  • Emerging challenges in understanding life, managing global systems, and healthcare diagnostics require broader applications.
  • The field must adapt its educational approach to address these complex, systems-level problems.

Purpose of the Study:

  • To review the essential role of analytical methods in guiding research in new scientific fields.
  • To explore how analytical chemistry education should evolve to meet contemporary challenges.
  • To highlight the utility of simple, adaptable analytical techniques in novel research areas.

Main Methods:

  • Review of existing literature and research trends.
  • Case studies illustrating the application of analytical methods in diverse fields.
  • Discussion of pedagogical approaches in analytical chemistry.

Main Results:

  • Analytical methods, including simple, on-the-spot techniques, are crucial for advancing research in areas like self-assembled monolayers, soft lithography, paper diagnostics, and self-assembly.
  • There is a need to balance teaching sophisticated instrumentation with fundamental principles of measurement and analysis.
  • Analytical chemistry's scope is expanding beyond molecular properties to encompass complex systems.

Conclusions:

  • Analytical chemistry plays a vital role in interdisciplinary research by providing essential measurement and analytical guidance.
  • Educational curricula must adapt to incorporate systems-level thinking and diverse applications of analytical techniques.
  • The development and application of adaptable, fundamental analytical methods remain critical for future scientific discovery.