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Related Concept Videos

Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

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Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

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Related Experiment Video

Updated: May 10, 2026

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice
09:50

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice

Published on: November 2, 2019

Chronic lymphedema due to constriction.

Ho Joong Jeong1, Ghi Chan Kim, Young-Joo Sim

  • 1Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan, Korea.

Lymphatic Research and Biology
|June 19, 2013
PubMed
Summary

A woman developed chronic lymphedema in her left arm after wearing a magnetic bracelet. Early diagnosis is crucial for managing this unusual case of upper extremity swelling.

Area of Science:

  • Medicine
  • Vascular Medicine
  • Lymphedema Research

Background:

  • Lymphedema is a chronic condition characterized by fluid accumulation and tissue swelling, often affecting the limbs.
  • Constrictive causes of lymphedema are less common than other etiologies like surgery or infection.
  • Unusual external constrictions can precipitate or exacerbate lymphatic system dysfunction.

Observation:

  • A 71-year-old woman presented with unilateral left upper extremity swelling.
  • The swelling began after sleeping with a magnetic health bracelet, suggesting external constriction.
  • Initial diagnostic workup, including laboratory and radiologic tests, revealed no abnormalities apart from the limb swelling.

Findings:

  • Lymphoscintigraphy confirmed lymphatic system compromise in the affected upper extremity.

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  • The patient was diagnosed with chronic lymphedema secondary to external constriction by the bracelet.
  • The condition was localized to the left arm, highlighting a specific constrictive etiology.
  • Implications:

    • This case underscores the importance of a thorough patient history to identify iatrogenic or environmental causes of lymphedema.
    • Magnetic health bracelets, while marketed for wellness, can pose a risk of inducing lymphatic compromise.
    • Complete decongestive therapy can offer mild improvement, but prevention and early identification of constrictive sources are paramount.