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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
A new left atrial appendage occluder (Lifetech LAmbre Device) for stroke prevention in atrial fibrillation
1Department of Medicine and Therapeutics, SH Ho Cardiovascular and Stroke Centre, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR. yylam@cuhk.edu.hk
Insights
Non-valvular atrial fibrillation (AF) increases stroke risk. The LAmbre device offers a new percutaneous left atrial appendage (LAA) closure option with improved delivery and repositioning capabilities for AF patients.
Area of Science:
- Cardiology
- Medical Devices
- Interventional Procedures
Background:
- Non-valvular atrial fibrillation (AF) is a prevalent arrhythmia linked to ischemic stroke.
- Percutaneous left atrial appendage (LAA) closure is a growing intervention for AF patients at high risk of stroke and bleeding.
- Existing LAA closure devices face limitations regarding sheath size and device maneuverability.
Purpose of the Study:
- To introduce and detail the novel LAmbre LAA occluder.
- To describe the unique features and procedural application of the LAmbre device.
Main Methods:
- The LAmbre device is a self-expanding occluder made of nitinol mesh and polyester membranes.
- It features an umbrella and cover connected by a central waist.
- The device is delivered via an 8-10 French sheath and allows full recapture and repositioning.
Main Results:
- The LAmbre device presents a new option for LAA closure.
- Its design facilitates easier delivery and enhanced maneuverability compared to existing devices.
- Detailed procedural steps for its application are discussed.
Conclusions:
- The LAmbre device offers potential advantages in percutaneous LAA closure.
- Its design addresses limitations of current devices, particularly sheath size and repositioning.
- Further clinical evaluation will determine its efficacy and safety in managing stroke risk in AF patients.
Abstract:
Non-valvular atrial fibrillation (AF) is the commonest cardiac arrhythmia which causes ischemic stroke. Percutaneous left atrial appendage (LAA) closure is increasingly performed in AF patients with high stroke and bleeding risks. WATCHMAN and Amplatzer Cardiac Plug are the two mostly implanted devices worldwide with good clinical results. However, the need for relatively large delivery sheaths (9-14 French) and limited recapture and repositioning capabilities remains problematic for both devices. LAmbre is a new; self-expanding LAA occluder constructed from a nitinol mesh and polyester membranes. It consists of an umbrella and a cover connected by a short central waist. The device is delivered by an 8-10 French sheath and has full recapture and repositioning capabilities. This report discussed in detail the novel features andprocedural steps for LAmbre device.

