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The effects of undifferentiated spondyloarthropathy on left ventricular systolic and diastolic function

Neslihan Albayrak1, Nihal A Bayram, Sukran Erten

  • 1Department of Cardiology, Ataturk Education and Research Hospital, Ankara, Turkey.

International Journal of Rheumatic Diseases
|June 19, 2013
PubMed

Insights

Patients with undifferentiated spondyloarthropathy (uSpA) show preserved left ventricular systolic function. However, some diastolic parameters are impaired, suggesting potential cardiac involvement in uSpA patients.

Area of Science:

  • Cardiology
  • Rheumatology
  • Echocardiography

Background:

  • Cardiovascular mortality is elevated in spondyloarthropathy (SpA) patients.
  • Undifferentiated SpA (uSpA) requires further investigation into cardiac function.
  • Tissue Doppler echocardiography (TDE) aids in assessing myocardial function.

Purpose of the Study:

  • To evaluate left ventricular systolic and diastolic functions in uSpA patients.
  • To compare cardiac function in uSpA patients with healthy controls.
  • To utilize TDE and conventional echocardiography for comprehensive assessment.

Main Methods:

  • 45 uSpA patients and 44 healthy controls were enrolled.
  • Two-dimensional, M-mode, pulsed-wave, and TDE were performed.
  • Key parameters including Sm, Em, Am, IVCTm, ETm, IVRTm, and MPI were measured.

Main Results:

  • uSpA patients exhibited significantly longer isovolumetric relaxation time (IVRT) and deceleration time (DT).
  • Early diastolic myocardial peak velocity (Em) was significantly lower in the lateral wall of uSpA patients.
  • Septal Em was lower and IVRT was longer in uSpA compared to controls.

Conclusions:

  • Left ventricular systolic function remains preserved in uSpA patients.
  • While diastolic dysfunction frequency was similar, parameter deterioration indicates possible cardiac involvement.
  • Further monitoring of cardiac function in uSpA is warranted.
Abstract

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