Related Experiment Video
Updated: May 10, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
Published on: July 21, 2023
Hisian pacing restores cardiac function
Gaojun Wu1, Yongxin Cai, Weijian Huang
1Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, China.
Abstract:
We report a 57-year-old male patient with dilated cardiomyopathy, NYHA function class III and complete left bundle branch block (CLBBB) who received cardiac resynchronization therapy using His-bundle pacing (HBP) when a left-ventricular lead could not be placed. In 10 months' follow up, his symptoms resolved rapidly, his QRS, left ventricular and left ventricular ejection fraction normalized. Recent reports support the conception that HBP may be an alternative or even better therapy for heart failure patients with CLBBB, especially if biventricular pacing is not feasible.
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