[Assessment of proteinuria]
Related Experiment Video
Updated: May 10, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
Albina Nowak1, Andreas L Serra
1Klinik und Poliklinik für Innere Medizin Universitätsspital Zürich. albina.nowak@usz.ch
Abstract:
Proteinuria is frequently found by general practitioners and is a possible sign of kidney disease. The insidious nature of many kidney diseases that develop without overt symptoms emphasize the clinical importance of urine analysis, both in screening and in monitoring of kidney pathology. Early detection of kidney disease plays a key role in preventing and progression of kidney disease. Thus, general practitioner can greatly contribute to early recognition and assessment of renal disease. Proteinuria may be benign or suggestive of glomerular disease. Patients with persistent proteinuria should be referred to a nephrologist for decisions regarding further management including renal biopsy. The standard urine dipstick detects only albumin and is not sensitive enough to detect non-albumins. Estimation of daily protein excretion using the total protein-to-creatinine ratio widely replaced the 24-hour urine measurement.
Related Concept Videos
Nephrotic Syndrome II : Assessment and Medical Management
Urine Studies I: Urinalysis
Serum Studies: Renal Function Tests
Nephrotic Syndrome I : Introduction
Diabetic Nephropathy
Nursing Assessment of the Genitourinary System II: Inspection and Palpation

