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Congenital osteofibrous dysplasia Campanacci: spontaneous postbioptic regression
Björn Jobke1, Klaus Bohndorf, Volker Vieth
1*Department of Radiology and Sarcoma Center Berlin-Brandenburg, HELIOS Klinikum Berlin-Buch §Institute for Pathology, Reference Center for Orthopedic Pathology, HELIOS Klinikum Emil-von-Behring, Stiftung Oskar-Helene-Heim, Berlin and Sarcoma Center Berlin-Brandenburg, Berlin †Department of Radiology, Klinikum Augsburg, Augsburg ‡Department of Clinical Radiology, Medical University Münster, Münster, Germany.
Abstract:
Osteofibrous dysplasia Campanacci is a rare benign bone tumor most frequently observed in young childhood. The exclusive localization in the tibia is very characteristic. The incidence of congenital primary bone tumors is an absolute rarity. We report a case of a newborn with a histologically proven osteofibrous dysplasia Campanacci at the tibia presenting a regular radiographic follow-up. After a small open biopsy and spontaneous minor fracture, the lesion rapidly remodeled within 1½ months and almost completely regressed with restutio ad integrum. Surgical intervention in this tumor entity at childhood age has been shown to have a high recurrence rate but due to lack of experience with newborns, guidelines do not exist. We analyze the radiologic and histologic differential diagnosis of juvenile adamantinoma and emphasize that congenital peripheral bone tumors should be treated conservatively when malignancy is excluded.
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