Related Experiment Video

Updated: May 10, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

Cold abscess of the thigh in an infant

D Mishra1, A Mohta, P Arora

  • 1Department of Pediatrics, Chacha Nehru Bal Chikitsalaya, Maulana Azad Medical College , Delhi, India.

Kathmandu University Medical Journal (KUMJ)
|June 19, 2013
PubMed

Insights

Local reactions to diphtheria-pertussis-tetanus (DPT) vaccines are typically mild. This report details a rare case of a primary tuberculous abscess developing after an intramuscular DPT injection.

Area of Science:

  • Pediatrics
  • Immunology
  • Infectious Diseases

Background:

  • Diphtheria-pertussis-tetanus (DPT) vaccination is a standard pediatric immunization.
  • Common adverse reactions to DPT are generally mild and localized.
  • Reactions typically manifest within 48 hours post-vaccination.

Observation:

  • A rare case of a serious adverse event following DPT vaccination is presented.
  • The patient developed a primary tuberculous abscess.
  • The abscess formation was associated with the intramuscular injection site.

Findings:

  • The study highlights an unusual complication of DPT vaccination.
  • A tuberculous abscess, a rare sequela, was diagnosed.
  • The intramuscular DPT injection was identified as a potential contributing factor.

Implications:

  • This case underscores the importance of considering rare diagnoses in vaccine adverse events.
  • Further investigation into potential mechanisms linking DPT injection and tuberculous abscess formation may be warranted.
  • Clinicians should remain vigilant for atypical presentations following immunization.

More Related Videos

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Temperature Measurement Sites01:14

Temperature Measurement Sites

A thermometer measures body temperature. The common sites for measuring body temperature are the oral cavity, axillary region, temporal artery, and skin surface, such as the forehead, abdomen, and axilla. True core body temperature is assessed in the rectum, tympanic membrane, pulmonary artery, esophagus, and urinary bladder.
Oral: When assessing oral temperature, the thermometer tip should be placed under the tongue in the posterior sublingual pocket. It offers accurate readings and can be...
Muscles that Move the Thigh01:20

Muscles that Move the Thigh

The thigh's motion is primarily governed by muscles originating in the pelvic girdle and inserted into the femur. One crucial muscle, the iliopsoas, is a combination of the psoas major and the iliacus muscles, sharing a common insertion point on the lesser trochanter of the femur.
Three other significant muscles are the gluteus maximus, gluteus medius, and gluteus minimus. The gluteus maximus originates from the posterior surface of the ilium, sacrum, and coccyx, and the thoracolumbar fascia...