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Related Experiment Video

Updated: May 10, 2026

Placing Growth Factor-Coated Beads on Early Stage Chicken Embryos

Placing Growth Factor-Coated Beads on Early Stage Chicken Embryos

Published on: October 1, 2007

Never too early for the opportunists!

Anup Subedee¹, William Kimmel, Anthony A Donato

¹Department of Medicine, Infectious Diseases Section, Tulane University School of Medicine, New Orleans, Louisiana, USA.

BMJ Case Reports

|June 19, 2013

Summary

Primary HIV infection can present with flu-like symptoms. In rare cases, it can also manifest as Pneumocystis pneumonia, responding well to trimethoprim-sulfamethoxazole treatment.

Area of Science:

Infectious Diseases
Immunology
Pulmonology

Background:

Primary HIV infection (PHI) affects 40-90% of newly infected individuals.
PHI symptoms are variable, often flu-like, with high viral load and decreased CD4 count.

Observation:

A homosexual man presented with PHI symptoms and a non-productive cough.
Chest CT revealed diffuse ground glass opacity.
Recent HIV seroconversion was confirmed.

Findings:

Pneumocystis jirovecii pneumonia (PJP) was diagnosed via transbronchial lung biopsy.
Symptoms rapidly improved with trimethoprim-sulfamethoxazole treatment.

Implications:

Pneumocystis pneumonia, typically an AIDS-defining illness, can occur during primary HIV infection.

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Last Updated: May 10, 2026

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Two-step Approach to Explore Early- and Late-stages of Organ Formation in the Avian Model: The Thymus and Parathyroid Glands Organogenesis Paradigm

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Early recognition and treatment of PJP in PHI are crucial for patient outcomes.