Related Experiment Video
Updated: May 10, 2026
10:35
Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
[Infected knee prostheses. Part 1: early infection or acute hematogenous infection]
P Herrmann1, P Thoele, V Heppert
1Abteilung Unfall-, Wirbelsäulen- und Gelenkchirurgie, Asklepios-Südpfalzklinik Kandel, Luitpoldstr. 14, 76870 Kandel, Germany. pe.herrmann@asklepios.com
Operative Orthopadie Und Traumatologie
|June 19, 2013
Summary
This study explores implant salvage for early total knee arthroplasty (TKA) infections. The described surgical technique achieved a 70% success rate in treating these challenging knee infections.
Area of Science:
- Orthopedic surgery
- Infectious disease management
- Biomaterials science
Context:
- Early postoperative infections following total knee arthroplasty (TKA) present a significant challenge.
- Prompt intervention is crucial for implant salvage and patient recovery.
- Distinguishing between early TKA infections and acute hematogenous infections is vital.
Purpose:
- To describe a surgical technique for salvaging total knee arthroplasty (TKA) implants in cases of early infection.
- To evaluate the efficacy of arthrotomy, synovectomy, inlay management, and polyhexanide irrigation for TKA infection treatment.
- To outline the postoperative management protocol aimed at maximizing implant survival and functional recovery.
Summary:
- The described salvage procedure involves arthrotomy, synovectomy, inlay removal/replacement, jet lavage with polyhexanide, and drainage.
- Postoperative management includes infusion-aspiration-drainage with polyhexanide, continuous passive motion (CPM), and progressive mobilization.
- This approach demonstrated a 70% success rate in salvaging TKA implants affected by early-stage infections.
Impact:
- Successful TKA implant salvage can prevent the need for revision surgery, reducing patient morbidity and healthcare costs.
- The findings provide valuable insights into effective treatment strategies for early TKA infections.
- This approach offers a potential solution for preserving joint function and improving patient outcomes after TKA.
Related Concept Videos
01:25Endocarditis I: Introduction
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
01:25Urinary Tract Infection II: Pathophysiology
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
01:27Acute Pyelonephritis I: Introduction
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
01:26Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...