Related Experiment Video
Updated: May 10, 2026
10:35
Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
[Infected knee prostheses. Part 2: chronic late infections]
P Herrmann1, P Thoele, V Heppert
1Abteilung Unfall-, Wirbelsäulen- und Gelenkchirurgie, Asklepios-Südpfalzklinik Kandel, Luitpoldstr. 14, 76870 Kandel, Germany. pe.herrmann@asklepios.com
Operative Orthopadie Und Traumatologie
|June 19, 2013
Summary
This study details treating chronic implant infections by removing infected material. The two-stage revision total knee arthroplasty (TKA) achieved an 81% success rate in complex cases.
Area of Science:
- Orthopedic Surgery
- Infectious Disease Management
- Biomaterials Science
Context:
- Chronic implant-associated infections pose significant challenges in orthopedic surgery.
- Treatment often necessitates radical debridement and implant removal.
- Late and chronic infections require comprehensive management strategies.
Purpose:
- To outline the surgical technique and postoperative management for late and chronic implant infections.
- To evaluate the success rate of a two-stage revision total knee arthroplasty (TKA) protocol.
- To identify indications and contraindications for this treatment approach.
Summary:
- The study describes a protocol for treating chronic infections requiring implant removal, including arthrotomy, debridement, spacer placement, and delayed reimplantation.
- Indications include infections >4 weeks with bacterial evidence.
- Contraindications involve acute sepsis, life-threatening bacteremia, and unreconstructable soft tissue defects.
Impact:
- The described two-stage revision TKA protocol demonstrates an 81% success rate in a challenging patient cohort.
- This approach offers a viable solution for complex cases where standard treatments fail.
- Effective management of chronic implant infections improves patient outcomes and joint function.
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