Solid-phase supports for oligonucleotide synthesis
1AM Chemicals LLC, Oceanside, California.
Current Protocols in Nucleic Acid Chemistry
|June 19, 2013
Abstract:
This unit attempts to provide a reasonably complete inventory of over 280 solid supports available to oligonucleotide chemists for preparation of natural and 3'-modified oligonucleotides. Emphasis is placed on non-nucleosidic solid supports. The relationship between the structural features of linkers and their behavior in oligonucleotide synthesis and deprotection is discussed wherever the relevant observations are available.
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