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Phenolic metabolites of benzene induced caspase-dependent cytotoxicities to K562 cells accompanied with decrease in

Yan Wang1, Guang-Yao Zhang, Qing-Ling Han

  • 1School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.

Environmental Toxicology
|June 19, 2013
PubMed
Summary

Benzene metabolites induce K562 cell apoptosis via caspase-8 and reactive oxygen species (ROS). Sialic acid metabolism alterations, particularly with hydroquinone and catechol, contribute to this process, impacting erythropoiesis.

Keywords:
apoptosisbenzene metabolitescaspasesreactive oxygen speciessialic acid

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