Related Experiment Video
Updated: May 10, 2026

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
Published on: March 5, 2022
Clinical characteristics of polycystic ovary syndrome in Indian women
Sunita J Ramanand1, Balasaheb B Ghongane, Jaiprakash B Ramanand
1Department of Pharmacology, Government Medical College, Miraj, Maharashtra, India.
Background:
Polycystic ovary syndrome (PCOS) is common diagnosis in women presenting with infertility. All the dimensions of PCOS have not been completely explored. Many studies have tried to characterize the exact presentation of the disease. In this study we studied clinical features of PCOS in Indian women to characterize different phenotypes of this syndrome. Prevalence of acanthosis nigricans (AN) as surrogate marker of insulin resistance, obesity, hirsutism and hypothyroidism in PCOS women have been simultaneously studied.
Materials And Methods:
Present work is a non comparative cross-sectional open label study carried out over a period of 18 months in an endocrinology hospital in western Maharashtra, India.
Results And Conclusion:
Authors conclude that PCOS occurs both in obese and non-obese women; AN and hirsutism occur in equal proportion of patients. AN is correlated with obesity. Hormonal dysfunctions in PCOS manifested together or independently. PCOS women can be sub grouped based on clinical features suggestive of endocrinological malfunctions and can be investigated accordingly for selection of appropriate treatment modalities.
Related Concept Videos
Disorders of the Female Reproductive System
Oogenesis
Infertility in Females
Endometriosis, a condition characterized by abnormal growth of endometrial...
Type I Diabetes III: Clinical Manifestations
Type II Diabetes I: Introduction
Hormonal Control of the Ovarian Cycle
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...

