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[Microdiathermocoagulation in the treatment of herpetic keratitis]
Abstract:
The authors analyze the efficacy of microdiathermocoagulation (MDC) in 126 patients with herpetic keratitis. Combined use of MDC and soft contact highly hydrophilic lenses preimpregnated with poludan, an interferon inductor solution, has helped reduce almost twofold the mean period of treatment of 80 patients with dendritic keratitis as compared to idoxuridine monotherapy. The study has shown the advantages of a soft contact lens over ointment dressing prescribed after such microsurgical manipulations to patients with superficial herpetic keratitis. A special microelectrode scarifier is suggested. The efficacy of MDC in the treatment of herpetic stromal keratitis with ulceration has been demonstrated, as well as in the management of superinfection manifestations (purulent ulcer, abscess of the cornea). The technique and the results of MDC are discussed and compared to mechanical abrasion and argon laser coagulation in herpetic keratitis.
Insights
Microdiathermocoagulation (MDC) combined with poludan-soaked contact lenses significantly speeds herpetic keratitis treatment. This approach offers advantages over traditional therapies for various herpetic keratitis forms.
Area of Science:
- Ophthalmology
- Virology
- Medical Technology
Background:
- Herpetic keratitis, a viral eye infection, poses significant treatment challenges.
- Traditional therapies like idoxuridine monotherapy have limitations in efficacy and treatment duration.
- Superinfection and stromal involvement complicate herpetic keratitis management.
Purpose of the Study:
- To evaluate the efficacy of microdiathermocoagulation (MDC) in treating herpetic keratitis.
- To assess the combined effect of MDC and poludan-soaked hydrophilic contact lenses.
- To compare MDC with other treatment modalities such as mechanical abrasion and argon laser coagulation.
Main Methods:
- Microdiathermocoagulation (MDC) was performed on 126 patients with herpetic keratitis.
- A subset of 80 patients with dendritic keratitis received combined MDC and poludan-soaked soft contact lenses.
- Treatment outcomes were compared to idoxuridine monotherapy, ointment dressing, mechanical abrasion, and argon laser coagulation.
Main Results:
- Combined MDC and poludan-soaked lenses reduced the mean treatment period by nearly half for dendritic keratitis compared to idoxuridine.
- MDC demonstrated efficacy in treating herpetic stromal keratitis with ulceration and superinfections.
- Soft contact lenses were found advantageous over ointment dressing post-MDC for superficial herpetic keratitis.
Conclusions:
- Microdiathermocoagulation, particularly when combined with poludan-soaked contact lenses, is an effective treatment for herpetic keratitis.
- MDC offers a viable alternative for managing complex herpetic keratitis cases, including stromal involvement and superinfections.
- The study suggests a novel microelectrode scarifier for MDC procedures.