Related Experiment Video

Updated: May 10, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Published on: July 6, 2013

Intractable diarrhoea caused by cytomegalovirus enterocolitis in an immunocompetent term neonate

Amit Kumar Gupta1, Arti Maria, Deepak Goyal

  • 1Department of Pediatrics, PGIMER & Dr RML Hospital, New Delhi 110001, India.

Journal of Tropical Pediatrics
|June 20, 2013
PubMed

Insights

Cytomegalovirus (CMV) can cause severe diarrhea in newborns. This case highlights that even healthy term infants can develop CMV enterocolitis, requiring prompt ganciclovir treatment.

Area of Science:

  • Neonatal Medicine
  • Infectious Diseases
  • Gastroenterology

Background:

  • Symptomatic cytomegalovirus (CMV) infection typically affects preterm and immunocompromised infants.
  • Common manifestations include rash, pneumonia, hepatosplenomegaly, and encephalitis.

Observation:

  • A case of intractable diarrhea at two weeks of age in an immunocompetent, term neonate is presented.
  • This diarrhea was caused by postnatally acquired cytomegalovirus (CMV) enterocolitis.

Findings:

  • This is the first reported case of intractable diarrhea due to postnatally acquired CMV in an immunocompetent term neonate.
  • The infant experienced protracted diarrhea suggestive of enterocolitis.

Implications:

  • Cytomegalovirus (CMV) should be considered in the differential diagnosis of intractable diarrhea in neonates.
  • Intravenous ganciclovir is indicated and therapeutic for cytomegalovirus (CMV) enterocolitis in neonates.

Keywords:
cytomegalovirusdiarrhoeaganciclovirneonate

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