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Paediatric active enhanced disease surveillance: a new surveillance system for Australia

Yvonne Zurynski1, Peter McIntyre, Robert Booy

  • 1Australian Paediatric Surveillance Unit, Kids Research Institute, The Sydney Children’s HospitalsNetwork (Westmead), Westmead, NSW 2145, Australia. yvonne.zurynski@health.nsw.gov.au

Journal of Paediatrics and Child Health
|June 21, 2013
PubMed

Insights

The Paediatric Active Enhanced Disease Surveillance (PAEDS) system collected data on severe childhood diseases and vaccine adverse events. This surveillance enhanced public health policy and clinical practice in Australia.

Area of Science:

  • Public Health
  • Epidemiology
  • Pediatrics

Background:

  • Gaps exist in surveillance for severe vaccine-preventable diseases in children.
  • Adverse events following immunisation require robust monitoring.
  • The Paediatric Active Enhanced Disease Surveillance (PAEDS) was established to address these needs.

Purpose of the Study:

  • To describe the Paediatric Active Enhanced Disease Surveillance (PAEDS) system.
  • To outline its role in monitoring severe vaccine-preventable diseases and adverse events.
  • To assess its effectiveness in data collection and public health impact.

Main Methods:

  • Active surveillance conducted in four tertiary children's hospitals across Australia (August 2007-December 2010).
  • Recruitment of children with acute flaccid paralysis, varicella, intussusception, infant seizures, and pandemic influenza.
  • Collection of detailed clinical, immunisation, and laboratory data; ascertainment audits performed.

Main Results:

  • 733 cases of target conditions and 601 influenza cases recruited.
  • PAEDS enhanced acute flaccid paralysis surveillance, meeting WHO targets.
  • Intussusception linked to rotavirus vaccination; varicella and seizure data provided insights into vaccine impact.

Conclusions:

  • PAEDS provides crucial, novel data for public health policy and clinical practice.
  • The system enhances community confidence in immunisation programs.
  • PAEDS demonstrates potential for rapid response during outbreaks and epidemics.
Abstract

Keywords:
childimmunisationinfectious diseasesurveillance system

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