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Related Concept Videos

Lethal Alleles02:41

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Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
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Related Experiment Video

Updated: May 10, 2026

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis
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Published on: January 14, 2017

Hairy polyp can be lethal even when small in size.

Yuhki Koike1, Keiichi Uchida, Mikihiro Inoue

  • 1Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Tsu, Mie, Japan. koikyon@gmail.com

Pediatrics International : Official Journal of the Japan Pediatric Society
|June 21, 2013
PubMed
Summary

A rare congenital hairy polyp caused sudden cardiopulmonary arrest in an infant due to respiratory distress. Early diagnosis is crucial, as small polyps pose a significant, potentially lethal, risk.

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Area of Science:

  • Pediatric Otolaryngology
  • Congenital Malformations
  • Respiratory Medicine

Background:

  • Hairy polyps are rare congenital benign tumors.
  • They can cause significant respiratory distress, especially in infants.
  • Sudden cardiopulmonary arrest is a potential life-threatening complication.

Observation:

  • A 3-month-old infant experienced recurrent respiratory distress and cardiopulmonary arrest.
  • Computed tomography and endoscopy identified a nasopharyngeal hairy polyp.
  • Histopathological analysis confirmed the diagnosis of a hairy polyp.

Findings:

  • Small hairy polyps (≤ 3.0 cm) are associated with a higher risk of respiratory distress compared to larger ones (P = 0.01).
  • Delayed diagnosis of small hairy polyps can lead to lethal outcomes.
  • Physical examination alone may miss small nasopharyngeal polyps.

Implications:

  • Physicians must consider hairy polyps in infants with unexplained respiratory distress.
  • Advanced imaging and endoscopic evaluation are essential for diagnosing small polyps.
  • Prompt surgical removal of hairy polyps is critical to prevent severe complications.