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Updated: May 10, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Reducing transfusion-associated malaria in Pakistan: an algorithmic approach.

Zain A Sobani¹, Sobia Nizami, Mehnaz Jabeen

¹Department of Biological and Biomedical Sciences, Aga Khan University, Pakistan.

Tropical Doctor

|June 21, 2013

Summary

Blood transfusions can transmit malaria. This study proposes an algorithm for malaria blood screening in Pakistan, combining donor history and regional risk to guide testing and reduce transmission.

Keywords:

Blood transfusion Pakistan diagnostic testing malaria

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Published on: November 2, 2018

Area of Science:

Infectious Diseases
Public Health
Transfusion Medicine

Background:

Blood transfusions are a potential route for malaria transmission.
Current screening relies on donor history, lacking in vitro testing guidelines in endemic regions.
Existing laboratory screening methods (microscopy, ELISA, PCR, rapid antigen tests) have limitations.

Purpose of the Study:

To develop evidence-based recommendations for malaria blood screening in Pakistan.
To propose an algorithmic approach integrating donor history and regional malaria endemicity.
To reduce the risk of transfusion-transmitted malaria.

Main Methods:

A best evidence review was conducted.
An algorithmic approach was developed for malaria blood screening.
The algorithm incorporates regional malaria endemicity and detailed donor history.

Main Results:

Recommendations are presented for an algorithmic approach to blood screening for malaria.
The algorithm guides decisions on using rapid antigen testing based on risk factors.
The proposed algorithm aims to enhance malaria detection in donor blood.

Conclusions:

An algorithmic approach can optimize malaria screening in blood banks.
Integrating donor history and endemicity data improves screening effectiveness.
The developed algorithm can inform national guidelines to prevent transfusion-transmitted malaria.