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Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

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In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging
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Subretinal abscess causing restricted diffusion on magnetic resonance imaging.

Crandall Peeler1, Hemant Parmar, Jonathan D Trobe

  • 1Departments of Ophthalmology and Visual Science, Kellogg Eye Center (CP, JDT), Radiology, Division of Neuroradiology (HP), and Neurology (JDT), University of Michigan, Ann Arbor, MI.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|June 21, 2013
PubMed
Summary
This summary is machine-generated.

Restricted diffusion on MRI can indicate subretinal abscess, a rare cause of vision loss. Early detection through diffusion-weighted imaging (DWI) aids timely treatment and vision preservation.

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Area of Science:

  • Ophthalmology
  • Neuroradiology
  • Medical Imaging

Background:

  • Restricted diffusion on diffusion-weighted imaging (DWI) is a key indicator of acute stroke and brain abscess.
  • Its presence in subretinal abscesses is rarely documented, with only one prior case reported.

Observation:

  • This study reviewed two cases of visual loss attributed to subretinal abscess.
  • Both cases exhibited restricted diffusion within the retinal abscess on DWI.

Findings:

  • The first case showed restricted diffusion in a visible posterior retinal mass.
  • The second case revealed restricted diffusion in an anterior retinal mass not detectable by ophthalmoscopy or ultrasound.
  • Combined with cerebral restricted diffusion suggesting septic emboli, these findings enabled prompt intervention.

Implications:

  • Diffusion-weighted imaging (DWI) can aid in the early diagnosis of subretinal abscess.
  • Timely diagnosis and treatment can preserve vision and prevent the need for enucleation.
  • This highlights the utility of advanced MRI techniques in diagnosing rare ocular pathologies.