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Related Concept Videos

Valence Bond Theory02:42

Valence Bond Theory

Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
Coordination Compounds and Nomenclature02:54

Coordination Compounds and Nomenclature

In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
Coordination Number and Geometry02:57

Coordination Number and Geometry

For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
Globular Proteins01:27

Globular Proteins

In organisms, proteins are the most abundant macromolecules. They act as the building blocks of life and play various crucial roles in the body. Proteins can be broadly classified into two distinct subtypes based on their shape and solubilities: globular proteins and fibrous proteins.
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Molecular Models02:00

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
Crystal Field Theory - Tetrahedral and Square Planar Complexes02:46

Crystal Field Theory - Tetrahedral and Square Planar Complexes

Tetrahedral Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...

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Synthesis of Compound Giant Unilamellar Vesicles: A Biomimetic Model of Nucleate Cells
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Giant hollow M(n)L(2n) spherical complexes: structure, functionalisation and applications.

Kate Harris1, Daishi Fujita, Makoto Fujita

  • 1Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Tokyo 113-8656, Japan.

Chemical Communications (Cambridge, England)
|June 21, 2013
PubMed
Summary
This summary is machine-generated.

Researchers designed self-assembled spherical coordination polyhedra inspired by virus capsids. These structures enable selective encapsulation and functionalization for advanced applications, including protein encapsulation.

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Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

Area of Science:

  • Supramolecular Chemistry
  • Coordination Chemistry
  • Nanotechnology

Background:

  • Nature utilizes hollow spherical structures like virus capsids and protein cages for efficient molecular organization.
  • Self-assembly is a key process in creating complex nanostructures from simple building blocks.

Purpose of the Study:

  • To design and synthesize novel self-assembled spherical coordination polyhedra.
  • To explore the functionalization and encapsulation capabilities of these synthetic structures.
  • To mimic and leverage natural self-assembly principles for advanced materials.

Main Methods:

  • Design of bent bis(pyridine) ligands with functional side chains.
  • Self-assembly of spherical coordination polyhedra (MnL2n) using Pd(2+) ions.
  • Characterization of exo- and endohedrally functionalized complexes.

Main Results:

  • Successful synthesis of a family of spherical coordination polyhedra.
  • Demonstration of facile exo- and endohedral functionalization.
  • Selective encapsulation of various guest molecules (metal ions, fluoroalkanes, fullerenes).
  • Application in size-controlled nanoparticle and polymer synthesis.
  • Encapsulation of a protein within the spherical framework.

Conclusions:

  • The designed spherical complexes offer tunable environments for molecular recognition and encapsulation.
  • These structures provide a platform for developing new functional materials and controlling biological functions.
  • The study highlights the potential of synthetic self-assembly to replicate and surpass natural nanoscale architectures.