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Conscientiousness and medication adherence: a meta-analysis
G J Molloy1, R E O'Carroll, E Ferguson
1School of Psychology, National University of Ireland Galway, Galway, Ireland, gerry.molloy@nuigalway.ie.
Background:
Approximately a quarter to a half of all people fail to take their medication regimen as prescribed (i.e. non-adherence). Conscientiousness, from the five-factor model of personality, has been positively linked to adherence to medications in several recent studies.
Purpose:
This study aimed to systematically estimate the strength and variability of this association across multiple published articles and to identify moderators of this relationship.
Method:
A literature search identified 16 studies (N = 3,476) that met the study eligibility criteria. Estimates of effect sizes (r) obtained in these studies were meta-analysed.
Results:
Overall, a higher level of conscientiousness was associated with better medication adherence (r = 0.15; 95 % CI, 0.09, 0.21). Associations were significantly stronger in younger samples (r = 0.26, 95 % CI, 0.17, 0.34; k = 7).
Conclusion:
The small association between conscientiousness and medication adherence may have clinical significance in contexts where small differences in adherence result in clinically important effects.
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