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Updated: May 10, 2026

Germ Cell Transplantation and Testis Tissue Xenografting in Mice
Published on: February 6, 2012
Classification, epidemiology and therapies for testicular germ cell tumours
Nikhil Vasdev1, Andrew Moon, Andrew C Thorpe
1Department of Urology, Freeman Hospital, Newcastle upon Tyne, United Kingdom. nikhilvasdev@doctors.org.uk
Abstract:
Testicular germ cell tumours (TGCT) account for between 1% and 1.5% of male neoplasms and 5% of urological tumours in general. They are classified broadly into Seminoma, which resemble primordial germ cells (PGCs), and Non-Seminoma, which are either undifferentiated (embryonal carcinoma) or differentiated (exhibiting a degree of embryonic (teratoma) or extra-embryonic (yolk sac choriocarcinoma) patterning). We present the current details of the latest classification, epidemiology and treatment aspects of TGCT in the UK in our review.
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