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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
07:11

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Echocardiographic features defining right dominant unbalanced atrioventricular septal defect: a multi-institutional

Meryl S Cohen1, Anusha Jegatheeswaran, Jeanne M Baffa

  • 1Cardiac Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. cohenm@email.chop.edu

Circulation. Cardiovascular Imaging
|June 21, 2013
PubMed

Insights

Defining right dominant unbalanced atrioventricular septal defect (AVSD) is challenging. New echocardiographic measures, particularly the right ventricle:left ventricle inflow angle, may help characterize unbalanced AVSD.

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease
  • Echocardiography

Background:

  • Right dominant unbalanced atrioventricular septal defect (AVSD) presents diagnostic and management challenges.
  • Left heart hypoplasia is a common feature of unbalanced AVSD.
  • The atrioventricular valve (AVV) index is a recognized echocardiographic measure for AVSD.

Purpose of the Study:

  • To identify additional echocardiographic features for characterizing right dominant unbalanced AVSD.
  • To differentiate between balanced and unbalanced forms of AVSD using echocardiography.

Main Methods:

  • Multi-institutional review of 52 preoperative echocardiograms of presumed right dominant unbalanced AVSD and 60 of balanced AVSD.
  • Cluster analysis and discriminant function analysis of echocardiographic variables.
  • Evaluation of variables including inflow angles, ventricular dimensions, and AVV measurements.

Main Results:

  • Three distinct patient groups were identified via cluster analysis.
  • The right ventricle:left ventricle inflow angle was the dominant differentiating variable (partial R²=0.86).
  • Other differentiating features included LV dimensions and AVV characteristics.

Conclusions:

  • The right ventricle:left ventricle inflow angle and other inflow surrogates are potential key echocardiographic measures for defining right dominant unbalanced AVSD.
  • Further confirmation of these findings is required.
Abstract

Keywords:
congenital heart diseaseechocardiographyendocardial cushion defects

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